Table 2 shows the results of the Cox univariate regression analysis for progression at any time. BMI (p = 0.022), male gender (p = 0.035), underlying ILD (p = 0.029) and continuous KL-6 (p = 0.017) were significantly associated with disease progression. Since both FVC and DLco at baseline were not associated with progression at any time, we did not perform a regression analysis with GAP index as predictor. When ILD type was included in the analysis, fNSIP was a protective factor for disease progression (p = 0.029). This evidence concerns the gene MUC1 and interstitial lung disease.