High levels of TGF-β are also correlated with the contractile capability of hyalocyte-containing collagen gels [24], and the increase of TGF-β levels following treatment with intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents is associated with the contraction of fibrovascular membranes in proliferative diabetic retinopathy and retinopathy of prematurity [25,26,27]. This evidence concerns the gene VEGFA and retinopathy of prematurity.