Jirapinyo et al. studied the effect of aspiration therapy on obesity-related comorbidities including NAFLD in 590 patients, and found that at one year there was a significant improvement in systolic blood pressure (−7.8 mm Hg; 95%CI −10.7 to −4.9), diastolic BP (−5.8 mm Hg; 95%CI −7.0 to 3.2), triglycerides (−15.8 mg/dL; 95%CI −24.0 to −7.6), HbA1c (−1.3%; 95%CI −1.8% to −0.8%) and ALT (−7.5 IU/L; 95%CI −9.8 to −5.2), as well as increase in HDL (3.6 mg/dL; 95%CI 0.7 to 6.6). Here, GPT is linked to metabolic dysfunction-associated steatotic liver disease.