TPO and hypothyroidism: Of note, the majority of thyroid involvement that has been studied in relation to alopecia involves anomalies of function (hypothyroidism or hyperthyroidism) and/or positive antithyroid antibodies, mainly TPO-Ab and Tg-Ab, which are consistent for Hashimoto’s thyroiditis and TR-Ab that offers the confirmation of Basedow-Graves’s disease.