Moreover, the levels of ALC (1.36 (0.99, 2.01) vs. 1.13 (0.80,1.63)), CRP (57.30 (9.80, 90.30) vs. 35.40 (8.51, 80.42)), IL-6 (70.30 (11.57, 101.99) vs. 42.53 (12.93, 64.47)), fibrinogen (4.95 (3.66, 5.66) vs. 3.97 (3.07, 4.98)), complement C3 (0.969 (0.852, 1.100) vs. 0.895 (0.765, 0.975)) and C4 (0.235 (0.191, 0.279) vs. 0.204 (0.163, 0.246)) in LC patients were much higher than those in patients without cancer (p < 0.05). Here, IL6 is linked to laryngotracheoesophageal cleft.