GPT and hyperuricemia: Figure 1 showed a flowchart of participant screening. The baseline characteristics of the patients were summarized in Table 1 and Table 2. Besides AIx and AIx@75, age, mean arterial pressure, urinary protein, TP, BUN, UA, TG, P, K, Mg, Fbg, HCY, D-Dimer, and the proportion of patients with hypertension, diabetes mellitus, hyperuricemia, and coronary heart disease (CHD) increased with the decrease of eGFR (p < 0.05). The levels of ALT, TC, HDL, Hb, PLT, and the proportion of ACEI/ARB, immunosuppressant, and glucocorticoid drug use were decreased with the decrease in eGFR (p < 0.05).