Multivariate analysis showed that age, institutionalization, congestive heart failure, dementia, higher SARS-CoV-2 Ct value (thus, lower viral loads), lower haemoglobin, higher white cell count, higher C-reactive protein and lower eGFR and lower albumin levels were associated with a higher risk of hypernatraemia in COVID-19 infection, after adjusting for confounding factors (Table 4). This evidence concerns the gene CRP and congestive heart failure.