Other frequently noted genes in combined SCLC are PTEN, TERT, ARID1B, SDHA, NF1, NOTCH2, NOTCH1, ALK, FGFR4, FGFR1, SOX2, NOTCH3, KMT2D, FAT1, and FAM135B [18,19]. The gene discussed is NOTCH3; the disease is small cell lung carcinoma.