THBS1 and endometriosis: For example, given the role of CD47 in tissue repair and in endometriosis, and particularly given that platelets, when activated, can release TSP-1 [144], we can deduce that platelet-derived TSP-1 can upregulate CD47 expression in adenomyotic lesions and reduce the phagocytosis efficiency of macrophages on adenomyotic stromal cells, as in endometriosis [124].