A recent cluster analysis using six variables (glutamate decarboxylase antibody, age at diagnosis, HbA1c, BMI, HOMA2-B, and HOMA2-IR) showed four T2DM clusters with distinctly different clinical characteristics and outcomes, such as diabetic complications [6,7,8,9,10,11,12,13,14,15,16,17,18]. The gene discussed is GLUL; the disease is type 2 diabetes mellitus.