On the contrary, other potential prognostic factors such as histopathological grade (G), gender, age, primary tumor size, Ki-67, cardiac surgery, stable disease due to somatostatin analogues use, peptide-receptor radionuclide therapy, coexistence of tricuspid regurgitation with pulmonary regurgitation and presence of bone metastasis were not significantly related to the OS in patients with CHD (Figure 3). Here, MKI67 is linked to pulmonary valve insufficiency.