S100A9 and pancreatic ductal adenocarcinoma: In addition, according to a proteomic study by Dr Wang, they found the upregulation of S100-A9, expressed predominantly in immune cells, such as granulocytes, monocytes, myeloid-derived suppressor cells, and other immature cells of the myeloid lineage, in pancreatic ductal adenocarcinoma tissues with diabetes compared with those without diabetes [29].