Based on the analyses of the expression profiles of lncRNA, miRNA, and mRNA (Supplementary Tables S1–S3), as well as the TMT data of NPC cells (CNE2R vs. CNE2) (Supplementary Table S4) and the gene chip data of clinical NPC samples (Supplementary Table S5), we proposed that a novel ceRNA network of CASC19/miR-340-3p/FKBP5 contributed to the radioresistance of NPC. The gene discussed is CASC19; the disease is nasopharyngeal carcinoma.