Analysis of correlation between the expression of genes Nr1d1, Fmr1, and Pten and the expression of all 795 C_AD DEGs showed that the expression of Nr1d1 correlates (r > 0.823; p < 0.001) with the expression of 314 DEGs, Fmr1 correlates with 358 DEGs, and Pten with 383 DEGs (Supplementary Table S5), indicating highly correlated changes in transcription levels of many DEGs found in the hippocampus of AD mice. This evidence concerns the gene PTEN and Alzheimer disease.