A stepwise logistic regression analysis comparing obesity with myostatin, age (both as dichotomic variables according to medians), and cirrhosis showed that myostatin was the only variable independently related to obesity, and the same happened when a multiple correlation analysis was performed between BMI as the dependent variable and myostatin, age, and the presence of cirrhosis (Table 3). This evidence concerns the gene MSTN and obesity due to melanocortin 4 receptor deficiency.