Among patients with obesity according to the OSA criteria, no differences were observed in myostatin values between patients with hypertension or diabetes when compared with patients without hypertension (T = 0.94; p = 0.36) or diabetes (T = 0.23; p = 0.82), and no significant relationships were observed between myostatin and cholesterol (ρ = 0.07, p = 0.70), triglycerides (ρ = 0.12, p = 0.53) or the index HDL/LDL cholesterol (ρ = 0.14; p = 0.45). This evidence concerns the gene MSTN and obstructive sleep apnea syndrome.