The fact that only men were included in this study may constitute another limitation of this research; however, on the other hand, although OSA criteria include different cut-off points for lean appendicular mass, handgrip strength, and obesity for men and women, relationships between myostatin and the crude DEXA-assessed simple variables could be distorted if men and women would have been analyzed together. The gene discussed is MSTN; the disease is obesity due to melanocortin 4 receptor deficiency.