The results obtained by Jia et al. can also be interpreted in various ways because it was reported that PKM2 is overexpressed in BC tissues, and this correlates with increased activation of AKT caused by PKM2-mediated phosphorylation of mTOR complex 1 (mTORC1) inhibitor, AKT1S1, and reduced autophagy [49]. The gene discussed is AKT1; the disease is breast cancer.