Sánchez-Romero et al. reported that the most visible changes after hip surgery in systemic biological markers, such as increased platelet and C-reactive protein concentrations, occur during days 1 to 3 postoperatively, and these may have an effect on some of the clinical outcomes, such as oedema, pyrexia, and postoperative pain that develop after surgery [26]. The gene discussed is CRP; the disease is edema.