Moreover, the activity of NF-κB in endometrial carcinoma promotes tumor cell migration, invasion, and metastasis via stimulation of Ras-related C3 botulinum toxin substrate 1 (Rac1), MMP-2 [24], and MMP-9 [21,23] transcription, and thus the basement membranes’ and ECM degradation, respectively [21,23]. This evidence concerns the gene MMP2 and neoplasm.