While other potentially relevant receptors, enzymes, cytokines, chemokines, or other signaling proteins have not yet been studied in the context of the NF-κB signaling pathway, which does not rule out their involvement in the pathogenesis of endometrosis, the need for further study of NF-κB signaling in endometrosis is indicated by the results of the latest research, according to which advanced endometrial fibrosis may be transformed into cancer [45]. The gene discussed is NFKB1; the disease is cancer.