CXCL8 and inflammatory bowel disease: The flavonoids (linarin, diosmetin-7-glucoside, and tilianin), phenolic acids, and polysaccharides of the chrysanthemum stem and leaf extract ameliorated the inflammatory bowel disease in zebrafish larvae exposed to sodium dextran sulfate (DSS), by regulating the expression of il1b, IL-8 (il8) and matrix metallopeptidase 9 (MMP-9, mmp9), and stimulating the superoxide dismutase activity [106].