Pinto et al. found a positive correlation between BGN and anti-apoptotic gene signatures (BCL2, BCL2L2, BCL2A1, IQSEC2, and BCL2L1) and an inverse correlation with pro-apoptotic gene signatures (CASP3, CASP6, CASP5, CASP8, CASP10, FASN, BAK, and BIK) in gastric cancer human samples [35]. The gene discussed is CASP5; the disease is gastric cancer.