To determine if the chromosome 3 GBPs restricted the intracellular growth of virulent Mtb, in addition to BCG, we quantified the growth of Mtb strain H37Rv in BMDMs from wild type, IFNγR−/− and Gbpchr3−/− animals in the presence and absence of IFNγ Figure 2A. We observed no differences in the uptake between genotypes four hours following infection. Here, IFNGR1 is linked to infection.