XIAP and neuroblastoma: Neuroprotection by hXIAP overexpression was also observed in the modified SH-SY5Y neuroblastoma cell line (SH-SY5YXIAP+), which preserved enough functionally active XIAP under pro-apoptotic conditions to reduce caspase cleavage and activity, reduce PARP cleavage, and increase cell survival against Sts and TG stimulation.