However, polymorphisms in the gene coding for IL-18 did not translate to increased incidence of BPD [183], but single nucleotide polymorphisms (SNPs) of the IL-18 receptors (IL-1R5 and IL-1R7) were associated with BPD in an African American (AA) (but not Caucasian) population [184]. The gene discussed is IL18; the disease is bronchopulmonary dysplasia.