SCL25A3 was found to be differentially expressed in sclerosis-prone ROP-Os/+ and sclerosis resistant C57-Os/+ mouse kidneys [91], and both SLC25A5 and SLCA25A6 genes are reported to be modulated in type 2 diabetic patients with end-stage renal disease [92]. Here, SLC25A5 is linked to stage 5 chronic kidney disease.