CYP24A1 and glaucoma: This family of enzymes to date, is divided in eight independent gene families (i.e., α, β, γ, δ, ζ, η, θ and ι-classes) Among the 15 known humans (h) CA isoforms belonging to class α, the cytosolic isoforms hCA I and hCA II are omnipresent in the body and represent the targets for anticonvulsant, diuretic, and anti-glaucoma drugs.