Recently, Ji et al. found that two independent SNPs in the 6p21.33 regions were associated with altered oral cancer risks in a Chinese population: rs2524182 (6:31130593) in TRIM39-RPP21-HLA-E and rs3131018 (6:31143582) in PSORS1C3-TCF19 [40]. The gene discussed is RPP21; the disease is lip and oral cavity carcinoma.