Therefore, to clarify the relationship between LAT1 and anti-cancer drug-induced mTOR activation, Western blotting was used to determine the protein expression of LAT1, mTOR, p-mTOR, p70S6K, and p-p70S6K in LAT1-suppressed CRC cells after treatment with oxaliplatin. The gene discussed is SLC7A5; the disease is colorectal carcinoma.