Conversely, one of the peptides that mainly characterised the RAS-mutant NIFTPs was Peptidylprolyl isomerase A (PPIA), also known as Cyclophilin A (CyPA), a ubiquitously distributed protein belonging to the immunophilin family, which is involved in the regulation of protein folding and trafficking with significant implications in different human diseases, including cancer [17]. The gene discussed is PPIA; the disease is cancer.