By querying the AACR Project GENIE (accessed on 20 January 2023, https://www.aacr.org/professionals/research/aacr-project-genie/; [105]) through the cBioPortal (accessed on 20 January 2023, https://www.cbioportal.org/; [106,107]), the GRIN2A gene was found to be altered (somatic mutations, copy number variation, and structural variants) in 4% of all cancers, with melanoma, bladder, lung, and colon adenocarcinoma having the greatest prevalence of alterations (Figure 5). The gene discussed is GRIN2A; the disease is melanoma.