Several groups including ours have reported the characterization of hMOs generated from idiopathic PD patients as well as those harboring PD-related mutations or variants including SNCA, LRRK2, PRKN/Parkin, PINK1, DNAJC6, and GBA1 that recapitulate key features of the disease (Supplementary Table S4). Here, LRRK2 is linked to Parkinson disease.