RHO and cancer: Functional annotation analysis of predicted targets for miR-218-5p, miR-31-5p and miR-199a-5p revealed several pathways and cellular processes potentially involved in CDDP-resistant phenotypes, including the Cadherin signalling pathway, angiogenesis, membrane trafficking MAPK and Wnt signalling pathway, RHO GTPase cycle, various pathways associated with cancer and interestingly, multiple times, axon guidance.