Although there is only a little knowledge about the relationship of ANGPTLs and inflammation in placentas at term, given that ANGPTLs have been related to inflammation [38] and that the placentas from women with GDM appear to be more inflamed [39], the observed changes in ANGPTL3 expression could also be partly due to this factor. The gene discussed is ANGPTL3; the disease is gestational diabetes.