Previous studies reported evidence for CYP2E1 as a marker of hepatocyte differentiation and a contributor to the pathogenesis of non-alcoholic steatohepatitis and hepatic cirrhosis due to its association with lipid peroxidation and the production of reactive oxygen species, as well as consecutive damage to cellular and mitochondrial membranes [42]. The gene discussed is CYP2E1; the disease is metabolic dysfunction-associated steatohepatitis.