Eight IAP proteins have been recognized: XIAP (Human X Chromosome-Encoded IAP), IAP-1/BIRC2 (baculoviral IAP repeat-containing 2), IAP-2/BIRC3, Liwin/BIRC7/ML-IAP (Melanoma IAP), BIRC8/ILP -2 (IAP-like Protein 2), NAIP (Neuronal Apoptosis-Inhibitory Protein), BRUCE/Apollon/BIRC6, and surviving/BIRC5 [10,11]. The gene discussed is BIRC8; the disease is melanoma.