MUC1 and chorioamnionitis: Progression of PE is believed to be associated with a general decrease in the synthesis of O-glycans carrying the sialyl-Tn antigen on such glycoproteins as mucin 1 (MUC1), CD44, integrins and osteopontin, which indirectly confirms the observed loss of MUC1 in the human placenta associated with inflammation during pregnancies with PE and chorioamnionitis [57].