TGFB1 and endometriosis: Bearing in mind the role of an important immune suppressor such as TGF-β1 in the activation of Th17 cells [87], as well as the release of that cytokine by the T-reg lymphocytes [88], the disturbance of the distribution and activation of the Treg and Th17 lymphocyte system in an inflammatory disease such as endometriosis may be related to the deregulation of TGF-β1 signaling in peripheral blood.