Although no association between the presence of TPO antibodies and self-reported stress in 759 euthyroid subjects was previously observed in the study by Strieder et al. [28], we found positive correlations between the number of major life events and life events with a negative impact on both TPO and Tg antibody levels, suggesting that stress might be involved in the progression/course of HT. The gene discussed is TPO; the disease is hematocrit.