The role of PC [52], PEp- [55], Q10 [52], purine metabolism [54] and immune-based regulation via RAS-RAF-MEK-MAPK pathway [35,36,37,38,39] were reported for HCC, which accounts for 80–90% of the adult cases of liver cancer [2]. The gene discussed is MAP2K7; the disease is hepatocellular carcinoma.