SLC38A1 and cancer: Among them, ASCT2 (SLC1A5), SNAT1 (SLC38A1) and SNAT2 (SLC38A2) play a major role in cancer cells, since ASCT2 is required for optimal growth at low glutamine concentrations, whereas SNAT1 and SNAT2 mainly mediate net glutamine uptake for glutaminolysis [4].