In all three adjusted analyses, there was no significant association between albumin administration and overall AKI (OR 1.26, 95% CI: 0.90–1.76 for the IPTW; OR 1.03, 95% CI: 0.72–1.48 for the PSM; and OR 1.04, 95% CI: 0.76–1.43 for the PS covariate adjustment methods); there was also no association with stage 2 and 3 AKI (OR 1.51, 95% CI: 0.83–2.75 for the IPTW; OR 1.53, 95% CI: 0.79–2.95 for the PSM; and OR 1.29, 95% CI: 0.72–2.29 for the PS covariate adjustment methods), although significant associations existed in the unadjusted cohorts. This evidence concerns the gene ALB and acute kidney injury.