APOC3 and myocardial infarction: While remnant cholesterol has been identified as a more determinant factor than LDL cholesterol in causing incident cardiovascular disease [47] and myocardial infarction [48], apoC-III is a functionally complex protein involved in several atherogenic processes, such as delayed lipoprotein removal, impaired triglyceride hydrolysis and increased adherence to the extracellular matrix.