CASP8 and T-cell non-Hodgkin lymphoma: Taken together, to the best of our knowledge, our results suggest, for the first time, that darinaparsin triggered a convergence of the intrinsic and extrinsic pathways of apoptosis via the activation of caspase-8 and cleaved Bid; though a previous study has previously suggested that treatment with darinaparsin results in activation of both extrinsic and intrinsic pathways in two T-cell lymphoma cell lines, Jurkat and Hut78 [26].