Administration of gallic acid extract from Terminalia bellirica fruit to mice ameliorated chronic mild stress-induced depression-like behavior by reduction of serum corticosterone and acetylcholinesterase (which led to regulation of hyperactivity of the hypothalamic-pituitary-adrenal axis), elevation of neurotransmitters, inhibition of monoamino oxidases (which led to modulation of the monoaminergic system), and mitigation of chronic mild stress-induced oxidative stress and apoptotic cell death [290]. Here, ACHE is linked to depressive disorder.