In our previous study, we have shown the bioconjugation of a Si-centered naphthalocyanine dye, with peripheral octabutoxy substitutions, to an anti-Epidermal growth factor receptor (EGFR; cetuximab) antibody for targeting over-expressed EGFR in tumor cells, which can potentially be used for PA imaging in deep-seated tumors [25,26]. This evidence concerns the gene EGFR and neoplasm.