LCAT and Cholestatic liver disease: Lipoprotein X (Lp-X) is an abnormal cholesterol-rich lipoprotein particle that can be found in familial lecithin:cholesterol acyltransferase deficiency, a rare genetic disease, and several hepatic disorders (primary biliary cirrhosis, primary sclerosing cholangitis, cholestatic liver disease, chronic alcoholism) with cholestatic liver disease [100].