The median OS of patients with high TIMP1 mRNA expression levels in myeloma cells (higher than median OS level of TIMP1 in patients with MM) tended to be shorter (3.3 years versus not reached), and the 3-year OS rate was inferior (55.7% versus 65%; p = 0.13), although the difference was not statistically significant. Here, TIMP1 is linked to Miyoshi myopathy.