Lastly, in the previously cited study by Laforce et al. [31], plasma biomarkers of neurodegeneration (NfL, Tau, GFAP, Ab42, and Ab42/Ab40 ratio) were all higher in the three cognitively impaired DM1 patients compared to the remaining noncognitively impaired DM1 patients (n = 9), while Ab40 plasma concentrations were similar between these two groups. The gene discussed is MAPT; the disease is myotonic dystrophy type 1.