Higher CerS6 levels were also observed in ER+ BCs with respect to ER- BCs [40,43,44], in Luminal BCs with respect to TNBCs and in epithelial-like cancer cells with respect to mesenchymal-like cancer cells [45], suggesting that the downregulation of CerS6 observed in the epithelial mesenchymal transition (EMT) might have a pivotal role in the regulation of cell migration. Here, CERS6 is linked to cancer.