CD9 and type 1 diabetes mellitus: Further stressing this notion, EVs of adipose MSCs from subjects with type 1 diabetes (T1D) are enlarged, reduced in number, and have a higher percentage of CD9 [112], and EVs from bone marrow MSCs obtained from aged mice contain high levels of miR-29-3p as compared with those isolated from younger mice and induce insulin resistance in acceptor young mice [113].