EIF4A1 and neoplasm: Furthermore, the TCGA data showed that in comparison to normal tissue, eIF4A1 expression was increased in all tumor grades, with grades 3 and 4 tumors revealing even higher levels than grades 1 and 2 tumors (Figure 1F; Normal vs. Grade 1: P = 2.359 × 10−03; Normal vs. Grade 2: P = 3.212 × 10−09; Normal vs. Grade 3: P = 4.581 × 10−09; Normal vs. Grade 4: P = 6.219 × 10−03; Grade 1 vs. Grade 3: P = 5.378 × 10−04; Grade 1 vs. Grade 4: P = 3.380 × 10−02; Grade 2 vs. Grade 3: P = 2.050 × 10−02; Grade 2 vs. Grade 4: P = 2.020 × 10−02).