In HCC (normal tissue: n = 50; tumor tissue: n = 371), eIF4A1 was significantly overexpressed (Figure 1A; LIHC: liver hepatocellular carcinoma; Figure 1B; P = 8.871× 10−10) with comparable incidences for women (P = 2.566 × 10−10) and men (P = 2.155 × 10−10; Figure 1C) and elevated expression for patients aged between 21 and 80 years (Figure 1D; 21–40 years: P = 1.463 × 10−06; 41–60 years: P = 2.841 × 10−08; 61–80 years: P = 7.070 × 10−09) compared to that in normal tissue. Here, EIF4A1 is linked to neoplasm.